Source: AGRICOLA database (1970-1996)

Arnholdt, S. B. (2000). RAPD analysis: A method to investigate aspects of the reproductive biology of Hypericum perforatum L. Theoretical and Applied Genetics. April 100(6): 906-911. {a} Departamento de Bioquimica e Biologia Molecular, Universidade Federal do Ceara, 60001-970, Fortaleza, CE, Brazil

Barone, G. W., B. J. Gurley, et al. (2000). Drug interaction between St. John's wort and cyclosporine. Annals of Pharmacotherapy. [print] September 34(9): 1013-1016. {a} Department of Surgery, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, 72205, USA

Biffignandi, P. M. and A. R. Bilia (2000). The growing knowledge of St. John's wort (Hypericum perforatum L) drug interactions and their clinical significance. Current Therapeutic Research. [print] July 61(7): 389-394. {a} Societa Italiana Attivita Farmaceutiche, Corso Re Umberto Ist, 44, 10128, Torino, Italy

Borchers, A. T., C. L. Keen, et al. (2000). Inflammation and Native American medicine: The role of botanicals. American Journal of Clinical Nutrition. [print] August 72(2): 339-347. {a} Division of Rheumatology/Allergy and Clinical Immunology, TB 192, School of Medicine, University of California at Davis, Davis, CA, 95616, USA

Bourke, C. A. (2000). Sunlight associated hyperthermia as a consistent and rapidly developing clinical sign in sheep intoxicated by St John's wort (Hypericum perforatum). Australian Veterinary Journal. [print] July 78(7): 483-488. {a} NSW Agriculture, Orange Agricultural Institute, Forest Road, Orange, NSW, 2800, Australia

Breidenbach, T., V. Kliem, et al. (2000). Profound drop of cyclosporin a whole blood trough levels caused by St. John's wort (Hypericum perforatum). Transplantation Baltimore. [print] May 69(10): 2229-2230. {a} Klinik fuer Viszeral- und Transplantationschirurgie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

Brenner, R., V. Azbel, et al. (2000). Comparison of an extract of hypericum (LI 160) and sertraline in the treatment of depression: A double-blind, randomized pilot study. Clinical Therapeutics. [print] April 22(4): 411-419. {a} St. John's Episcopal Hospital, South Shore, 327 Beach Street 19th Street, Far Rockaway, NY, 11691, USA

Briskin, D. P., A. Leroy, et al. (2000). Influence of nitrogen on the production of hypericins by St. John's wort. Plant Physiology and Biochemistry Paris. [print] May 38(5): 413-420. {a} Laboratory of Plant Biochemistry and Photobiology, Department of Natural Resources and Environmental Sciences, University of Illinois, Urbana, IL, 61801, USA

Brutovska, R., E. Cellarova, et al. (2000). Cytogenetic characterization of three Hypericum species by in situ hybridization. Theoretical and Applied Genetics. [print] July 101(1-2): 46-50. {a} Institut fuer Pflanzengenetik und Kulturpflanzenforschung (IPK), Corrensstrasse 3, D-06446, Gatersleben, Germany

Brutovska, R., P. Kusnirikova, et al. (2000). Karyotype analysis of Hypericum perforatum L. Biologia Plantarum Prague. [print] 43(1): 133-136. {a} Faculty of Science, Department of Experimental Botany and Genetics, P.J. Safarik University, Manesova 23, 041 67, Kosice, Slovakia

Budzinski, J. W., B. C. Foster, et al. (2000). An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine Jena. [print] July 7(4): 273-282. {a} Ottawa-Carleton Institute of Biology, Department of Biology, University of Ottawa, 30 Marie Curie St., Stn. A, Ottawa, ON, PO Box 450, K1N 6N5, Canada

Butterweck, V., G. Juergenliemk, et al. (2000). Flavonoids from Hypericum perforatum show antidepressant activity in the forced swimming test. Planta Medica. Feb. 66(1): 3-6. {a} Institut fuer Pharmakologie und Toxikologie, Westfaelische Wilhelms-Universitaet, Domagkstr. 12, D-48149, Muenster, Germany

Campbell, M. H. and H. I. Nicol (2000). Effect of split applications of herbicides on the control of Hypericum perforatum L. (St. John's wort) and regeneration of native grasses and annual clovers on non-arable land. Plant Protection Quarterly. [print] 15(3): 119-122. {a} NSW Agriculture, Orange Agricultural Institute, Orange, NSW, 2800, Australia

Carai, M. A. M., R. Agabio, et al. (2000). Potential use of medicinal plants in the treatment of alcoholism. Fitoterapia . [print] August 71(Supplement 1): S38-S42. {a} C.N.R. Center for Neuropharmacology, Cagliari, Italy

Cheng, T. O. (2000). St John's wort interaction with digoxin. Archives of Internal Medicine. [print] September 160(16): 2548. {a} Washington, DC, USA

Denke, A., H. Schempp, et al. (2000). Biochemical activities of extracts from Hypericum perforatum L.: 5th communication: Dopamine-beta-hydroxylase-product quantification by HPLC and inhibition by hypericins and flavonoids. Arzneimittel Forschung. [print] Mai 50(5): 415-419. {a} Lehrstuhl fuer Phytopathologie, Labor fuer Angewandte Biochemie, Technische Universitaet Muenchen, 85350, Freising-Weihenstephan, Germany

Di, M. V., G. G. Di, et al. (2000). Effect of acute administration of Hypericum perforatum-CO2 extract on dopamine and serotonin release in the rat central nervous system. Pharmacopsychiatry . Jan. 33(1): 14-18. {a} Consorzio 'Mario Negri' Sud, Istituto di Ricerche Farmacologiche 'Mario Negri', 66030, Santa Maria Imbaro, Chieti, Italy

Fisunov, A., N. Lozovaya, et al. (2000). Hyperforin modulates gating of P-type Ca2+ current in cerebellar Purkinje neurons. Pfluegers Archiv European Journal of Physiology. [print] July 440(3): 427-434. {a} Department of Cellular Membranology, Bogomoletz Institute of Physiology, 4 Bogomoletz Street, Kiev, 252024, Ukraine

Helgason, C. M., F. J. L. Wieseler, et al. (2000). The effects of St. John's Wort (Hypericum perforatum) on NK cell activity in vitro. Immunopharmacology . March 46(3): 247-251. {a} Department of Pathology and Microbiology, UNMC, 986495 Nebraska Medical Center, Omaha, NB, 68198-6495, USA

Kazarinova, N. V. and K. G. Tkachenko (2000). Medicinal plants in treatment of different forms of tuberculosis (review of Russian-language literature). Rastitel'nye Resursy 36(1): 92-106.

Kirakosyan, A., H. Hayashi, et al. (2000). Stimulation of the production of hypericins by mannan in Hypericum perforatum shoot cultures. Phytochemistry Oxford. Feb. 53(3): 345-348. {a} Department of Pharmacognosy, Gifu Pharmaceutical University, 5-6-1 Mitahora-higashi, Gifu, 502-8585, Japan

Kitanov, G. (2000). The dynamics and content of hypericins in Hypericum perforatum L. and Hypericum maculatum Crantz growing in Bulgaria. Acta Pharmaceutica Zagreb. [print] March 50(1): 65-68. {a} Department of Pharmacognosy Faculty of Pharmacy, Medical University of Sofia, Dunav Str. 2, 1000, Sofia, Bulgaria

Kulevanova, S., M. Stefova, et al. (2000). Determination of total flavonoids and quercetin in Hyperici herba and its aqueous, aqueous-ethanolic and oil extracts. Acta Pharmaceutica Zagreb. [print] March 50(1): 29-37. {a} Faculty of Pharmacy, Institute of Pharmacognosy, Vodnjanska 17, 91000, Skopje, Macedonia

Kumar, V., P. N. Singh, et al. (2000). Effect of Indian Hypericum perforatum Linn on animal models of cognitive dysfunction. Journal of Ethnopharmacology. [print] September 72(1-2): 119-128. {a} Neuropharmacology Laboratory, Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, 221 005, India

Liu, F. F., C. Y. W. Ang, et al. (2000). Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation. Journal of Chromatography A. [print] 888(1-2): 85-92. {a} National Center for Toxicological Research, Division of Chemistry, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR, 72079, USA

Liu, F. F., C. Y. W. Ang, et al. (2000). Optimization of extraction conditions for active components in Hypericum perforatum using response surface methodology. Journal of Agricultural and Food Chemistry. [print] August 48(8): 3364-3371. {a} Division of Chemistry, National Center for Toxicological Research, Food and Drug Administration, 3900 NCTR Road, Jefferson, AR, 72079, USA

Mai, I., H. Krueger, et al. (2000). Hazardous pharmacokinetic interaction of Saint John's wort (Hypericum perforatum) with the immunosuppressant cyclosporin. International Journal of Clinical Pharmacology and Therapeutics. [print] Oktober 38(10): 500-502. {a} Institute of Clinical Pharmacology, Charite University Medical Center, Humboldt University of Berlin, D-10098, Berlin, Germany

Makovetskaya, E. Y. (2000). Study of bound polyphenols in St. John's wort grass. Khimiko Farmatsevticheskii Zhurnal. Feb. 34(2): 55.

Markowitz, J. S., C. L. DeVane, et al. (2000). Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers. Life Sciences. Jan. 66(9): 133-139. {a} Department of Pharmaceutical Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA

Mauri, P. and P. Pietta (2000). High performance liquid chromatography/electrospray mass spectrometry of Hypericum perforatum extracts. Rapid Communications in Mass Spectrometry 14(2): 95-99. {a} Istituto Tecnologie Biomediche Avanzate/CNR, Via Fratelli Cervi,, 93-20090, Segrate (Milano), Italy

Michelitsch, A., B. Biza, et al. (2000). Determination of hypericin in herbal medicine products by differential pulse polarography. Phytochemical Analysis. Jan. Feb. 11(1): 41-44. {a} Institut fuer Pharmazeutische Chemie, Karl-Franzens-Universitaet Graz, Schubertstrasse 1, A-8010, Graz, Austria

Moore, L. B., B. Goodwin, et al. (2000). St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proceedings of the National Academy of Sciences of the United States of America. [print] June 97(13): 7500-7502. {a} Department of Molecular Endocrinology, Glaxo Wellcome Research and Development, 5 Moore Drive, Research Triangle Park, NC, 27709, USA

Murch, S. J., K. L. Choffe, et al. (2000). Thidiazuron-induced plant regeneration from hypocotyl cultures of St. John's wort (Hypericum perforatum. cv 'Anthos'). Plant Cell Reports. [print] May 19(6): 576-581. {a} Department of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada

Murch, S. J., S. KrishnaRaj, et al. (2000). Tryptophan is a precursor for melatonin and serotonin biosynthesis in in vitro regenerated St. John's wort (Hypericum perforatum L. cv. Anthos) plants. Plant Cell Reports. [print] June 19(7): 698-704. {a} Department of Plant Agriculture, Biotechnology Division, University of Guelph, Edmund C. Bovey Complex, Guelph, ON, N1G 2W1, Canada

Muruganandam, A. V., S. Ghosal, et al. (2000). The role of xanthones in the antidepressant activity of Hypericum perforatum involving dopaminergic and serotonergic systems. Biogenic Amines. [print] 15(5): 553-567. {a} Neuropharmacology Lab. Dept. Pharmacology, IMS, BHU, Varanasi, 221 005, India

Obach, R. S. (2000). Inhibition of human cytochrome P450 enzymes by constituents of St. John's wort, an herbal preparation used in the treatment of depression. Journal of Pharmacology and Experimental Therapeutics. [print] July 294(1): 88-95. {a} Drug Metabolism Department, Candidate Synthesis, Enhancement, and Evaluation, Central Research Division, Pfizer, Inc., Groton, CT, 06340, USA

Panocka, I., M. Perfumi, et al. (2000). Effects of Hypericum perforatum extract on ethanol intake, and on behavioral despair: A search for the neurochemical systems involved. Pharmacology Biochemistry and Behavior. [print] May 66(1): 105-111. {a} Department of Pharmacological Sciences, and Experimental Medicine, University of Camerino, 62032, Camerino (MC), Italy

Putnam, M. L. (2000). First report of leaf blight and stem dieback of St. John's-wort caused by Diploceras hypericinum in Oregon. Plant Disease. [print] November 84(11). {a} Botany and Plant Pathology, Oregon State University, Corvallis, OR, 97331-2903, USA

Schempp, C. M., R. Luedtke, et al. (2000). Effect of topical application of Hypericum perforatum extract (St. John's wort) on skin sensitivity to solar simulated radiation. Photodermatology Photoimmunology and Photomedicine. [print] June 16(3): 125-128. {a} Department of Dermatology, Photodermatology Unit, University of Freiburg, Haupstr. 7, D-79104, Freiburg, Germany

Schempp, C. M., B. Winghofer, et al. (2000). Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells. British Journal of Dermatology. [print] May 142(5): 979-984. {a} Department of Dermatology, Photodermatology Unit, University Medical Center, Haupstr 7, D-79104, Freiburg, Germany

Sun, W., X. F. Shi, et al. (2000). Preliminary determination of hypericin in Hypericum perforatum extract by HPLC. Zhongguo Yiyao Gongye Zazhi. [print] April 31(4): 172-173. {a} School of Biotechnology, Wuxi University of Light Industry, Wuxi, 214063, China

Taylor, L. v. and K. A. Kobak (2000). An open-label trial of St. John's wort (Hypericum perforatum) in obsessive-compulsive disorder. Journal of Clinical Psychiatry. [print] August 61(8): 575-578. {a} Dean Foundation for Health Research and Education, 2711 Allen Blvd., Middleton, WI, 53562, USA

Vandenbogaerde, A., P. Zanoli, et al. (2000). Evidence that total extract of Hypericum perforatum affects exploratory behavior and exerts anxiolytic effects in rats. Pharmacology Biochemistry and Behavior. April 65(4): 627-633. {a} Dipartimento di Scienze Farmaceutiche, Universita degli studi di Modena e Reggio Emilia, Via Campi 183, I-41100, Modena, Italy

Vormfelde, S. V. and W. Poser (2000). Hyperforin in extracts of St John's wort (Hypericum perforatum) for depression. Archives of Internal Medicine. [print] September 160(16): 2548-2549. {a} Goettingen, Germany

Wentworth, J. M., M. Agostini, et al. (2000). St John's wort, a herbal antidepressant, activates the steroid X receptor. Journal of Endocrinology. [print] September 166(3): R11-R16. {a} Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK

Woelk, H. (2000). Comparison of St John's wort and imipramine for treating depression: Randomised controlled trial. BMJ . [print] 321(7260): 536-539. {a} Klinik fuer Psychiatrie und Psychotherapie, Akademisches Lehrkrankenhaus der Universitaet Giessen, Licher Strasse 106, D-35394, Giessen, Germany

Yu, P. H. (2000). Effect of the Hypericum perforatum extract on serotonin turnover in the mouse brain. Pharmacopsychiatry . March 33(2): 60-65. {a} Neuropsychiatry Research Unit, Department of Psychiatry, University of Saskatchewan, Saskatoon, SK, S7N5E4, Canada

Al, K. A. S. and A. I. A. Al (1999). Physicochemical characteristics and pollen spectrum of some Saudi honeys. Food Chemistry. Oct. 67(1): 21-25. {a} Food Science and Nutrition Department, College of Agriculture, King Saud University, Riyadh, Saudi Arabia

Bernd, A., S. Simon, et al. (1999). Phototoxic effects of Hypericum extract in cultures of human keratinocytes compared with those of psoralen. Photochemistry and Photobiology 69(2): 218-221. {a} Dep. Dermatology, Clinical Hospital J. W. Goethe Univ., Theodor-Stern-Kai 7, D-60590 Frankfurt/M., Germany

Bezakova, L., M. Psenak, et al. (1999). Effect of dianthrones and their precursors from Hypericum perforatum L. on lipoxygenase activity. Pharmazie . Sept. 54(9): 711. {a} Department of Cell and Molecular Biology of Drugs, Odbojarov 10, 83232, Bratislava, Slovakia

Bork, P. M., S. Bacher, et al. (1999). Hypericin as a non-antioxidant inhibitor of NF-kappaB. Planta Medica. May 65(4): 297-300. {a} Institut fuer Pharmazeutische Biologie, Albert-Ludwigs Universitaet, Schaenzlestr. 1, D-79104, Freiburg, Germany

Calapai, G., A. Crupi, et al. (1999). Effects of Hypericum perforatum on levels of 5-hydroxytryptamine, noradrenaline and dopamine in the cortex, diencephalon and brainstem of the rat. Journal of Pharmacy and Pharmacology. June 51(6): 723-728. {a} School of Medicine, Institute of Pharmacology, University of Messina, Piazza XX Settembre 4, I-98122, Messina, Italy

Cellarova, E. and K. Kimakova (1999). Morphoregulatory effect of plant growth regulators on Hypericum perforatum L. seedlings. Acta Biotechnologica 19(2): 163-169. {a} Faculty of Science, Department of Experimental Botany and Genetics, P. J. Safarik University, Manesova 23, 041 67, Kosice, Slovakia

Chatterjee, S., V. Filippov, et al. (1999). Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat. Life Sciences. Oct. 65(22): 2395-2405. {a} Department of Cellular Membranology, Bogomoletz Institute of Physiology, Bogomoletz str.4, 252024, Kiev, Ukraine

Chi, J. D. and M. Franklin (1999). Measurement of hyperforin a constituent of St. John's wort in plasma by high-performance liquid chromatography. Journal of Chromatography B. Dec. 735(2): 285-288. {a} Department of Psychiatry, Psychopharmacology Research Unit, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK

Chi, J. D. and M. Franklin (1999). Determination of hypericin in plasma by high-performance liquid chromatography. Journal of Chromatography B 724(1): 195-198. {a} Department of Psychiatry, Psychopharmacology Research Unit, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK

De, V. J., S. Maurel, et al. (1999). Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism. European Neuropsychopharmacology. Dec. 9(6): 461-468. {a} CNS Research, Bayer AG, Aprather Weg 18, D-42096, Wuppertal, Germany

Denke, A., H. Schempp, et al. (1999). Biochemical activities of extracts from Hypericum perforatum L.: 4th communication: Influence of different cultivation methods. Arzneimittel Forschung. Feb. 49(2): 120-125. {a} Phytopathologie, Technische Universitaet Muenchen, D-85350, Freising-Weihenstephan, Germany

Denke, A., W. Schneider, et al. (1999). Biochemical activities of extracts from Hypericum perforatum L.: 2nd communication: Inhibition of metenkephaline- and tyrosine-dimerization. Arzneimittel Forschung. Feb. 49(2): 109-114. {a} Phytopathologie, Technische Universitaet Muenchen, D-85350, Freising-Weihenstephan, Germany

Fox, L. R., S. P. Ribeiro, et al. (1999). Direct and indirect effects of climate change on St John's wort, Hypericum perforatum L. (Hypericaceae). Oecologia Berlin. July 120(1): 113-122. {a} Biology Department, A316 EMS, University of California, Santa Cruz, CA, 95064, USA

Franklin, M., J. Chi, et al. (1999). Neuroendocrine evidence for dopaminergic actions of Hypericum extract (LI 160) in healthy volunteers. Biological Psychiatry. Aug. 46(4): 581-584. {a} University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, UK

Fugh, B. A. and J. M. Cott (1999). Dietary supplements and natural products as psychotherapeutic agents. Psychosomatic Medicine. Sept. Oct. 61(5): 712-728. {a} National Institute of Mental Health, 6001 Executive Blvd., room 7157, Bethesda, MD, 20892-9635, USA

Gambarana, C., O. Ghiglieri, et al. (1999). Efficacy of an Hypericum perforatum (St. John's Wort) extract in preventing and reverting a condition of escape deficit in rats. Neuropsychopharmacology . Aug. 21(2): 247-257. {a} Pharmacology Unit, Institute of Clinica delle Malattie Nervose e Mentali, Via Aldo Moro, 4, 53100, Siena, Italy

Gobbi, M., F. D. Valle, et al. (1999). Hypericum perforatum L. extract does not inhibit 5-HT transporter in rat brain cortex. Naunyn Schmiedeberg's Archives of Pharmacology. [print] Sept 360(3): 262-269. {a} Istituto di Ricerche Farmacologiche "Mario Negri", Via Eritrea 62, I-20157, Milan, Italy

Grice, I. D., M. Salzmann, et al. (1999). Simultaneous determination of aldrin, dieldrin, endrin, heptachlor, and p,p'-DDT in medicinal plant extracts using a novel high performance liquid chromatography method. Journal of Liquid Chromatography and Related Technologies. Sept. 22(15): 2337-2344. {a} School of Health Science, Griffith University, Gold Coast, QLD, 4217, Australia

Johne, A., J. Brockmoeller, et al. (1999). Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum). Clinical Pharmacology and Therapeutics. Oct. 66(4): 338-345. {a} Charite, Institute of Clinical Pharmacology, Humboldt University of Berlin, Schumannstrasse 20/21, D-10098, Berlin, Germany

Josey, E. S. and R. L. Tackett (1999). St. John's wort: A new alternative for depression? International Journal of Clinical Pharmacology and Therapeutics 37(3): 111-119. {a} Clinical and Administrative Sciences, College of Pharmacy, University of Georgia, Athens, GA, 30602, USA

Kaehler, S. T., C. Sinner, et al. (1999). Hyperforin enhances the extracellular concentrations of catecholamines, serotonin and glutamate in the rat locus coeruleus. Neuroscience Letters 262(3): 199-202. {a} Department of Pharmacology and Toxicology, University of Innsbruck, Peter-Mayr-Strasse 1, A-6020, Innsbruck, Australia

Keller, M. and J. Kollmann (1999). Effects of seed provenance on germination of herbs for agricultural compensation sites. Agriculture Ecosystems and Environment 72(1): 87-99. {a} Geobotanisches Inst., ETH Zurich, Zuerichbergstr. 38, CH-8044 Zurich, Switzerland

Kim, H. L., J. Streltzer, et al. (1999). St. John's wort for depression: A meta-analysis of well-defined clinical trials. Journal of Nervous and Mental Disease. Sept. 187(9): 532-539. {a} Department of Psychiatry, John A. Burns School of Medicine, University of Hawaii, 1356 Lusitana St., 4th Floor, Honolulu, HI, 96813, USA

Kleber, E., T. Obry, et al. (1999). Biochemical activities of extracts from Hypericum perforatum L.: 1st communication: Inhibition of dopamine-beta-hydroxylase. Arzneimittel Forschung. Feb. 49(2): 106-109. {a} Phytopathologie, Technische Universitaet Muenchen, D-85350, Freising-Weihenstephan, Germany

Kumar, V., A. K. Jaiswal, et al. (1999). Anxiolytic activity of Indian Hypericum perforatum Linn: An experimental study. Indian Journal of Experimental Biology. Jan. 38(1): 36-41. {a} Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India

Kumar, V., P. N. Singh, et al. (1999). Antidepressant activity of Indian Hypericum perforatum Linn in rodents. Indian Journal of Experimental Biology. Dec. 37(12): 1171-1176. {a} Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India

Liu, W. Z. and Z. H. Hu (1999). The secretory structure of Hypericum perforatum and its relation to hypericin accumulation. Acta Botanica Sinica. April 41(4): 369-372. {a} Institute of Botany, Northwest University, Xi'an, 710069, China

Neary, J. T. and Y. Bu (1999). Hypericum LI 160 inhibits uptake of serotonin and norepinephrine in astrocytes. Brain Research 816(2): 358-363. {a} Res. Serv. 151, VA Med. Cent., 1201 NW 16th St., Miami, FL 33125, USA

Ondrizek, R. R., P. J. Chan, et al. (1999). Inhibition of human sperm motility by specific herbs used in alternative medicine. Journal of Assisted Reproduction and Genetics 16(2): 87-91. {a} Department of Gynecology and Obstetrics, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA

Ondrizek, R. R., P. J. Chan, et al. (1999). An alternative medicine study of herbal effects on the penetration of zona-free hamster oocytes and the integrity of sperm deoxyribonucleic acid. Fertility and Sterility 71(3): 517-522. {a} Dep. Gynecol., and Obstet., Loma Linda Univ. Sch. Med., Lomda Linda, CA 92350, USA

Orth, H. C. J., C. Rentel, et al. (1999). Isolation, purity analysis and stability of hyperforin as a standard material from Hypericum perforatum L. Journal of Pharmacy and Pharmacology 51(2): 193-200. {a} Department of Pharmaceutical Technology, Eberhard-Karls University, Auf der Morgenstelle 8, D-72076, Tuebingen, Germany

Park, S. H. (1999). Unrecorded naturalized plants in Korea (XIV). Korean Journal of Plant Taxonomy. March 29(1): 91-109. {a} Inchang High School, 70 Chungjeong-ro 2-ga, Seodaemun-ku, Seoul, 120-012, South Korea

Perfumi, M., R. Ciccocioppo, et al. (1999). Effects of Hypericum perforatum extract on alcohol intake in Marchigian Sardinian alcohol-preferring rats. Alcohol and Alcoholism. Sept. Oct. 34(5): 690-698. {a} Department of Pharmacological Sciences and Experimental Medicine, University of Camerino, 62032, Camerino (MC), Italy

Pilegaard, K. and O. Ladefoged (1999). Wild plants causing intoxication in husbandry animals. Dansk Veterinaertidsskrift. Aug. 82(15): 666-668. {a} Institut for Fodevaresikkerhed og Toksikologi, Fodevaredirektoratet, Morkhoj Bygade 19, 2860, Soborg, Denmark

Rezvani, A. H., D. H. Overstreet, et al. (1999). Attenuation of alcohol intake by extract of Hypericum perforatum (St John's Wort) in two different strains of alcohol-preferring rats. Alcohol and Alcoholism. Sept. Oct. 34(5): 699-705. {a} Duke University Medical Center, Durham, NC, 27710, USA

Schempp, C. M., K. Pelz, et al. (1999). Antibacterial activity of hyperforin from St John's wort, against multiresistant Staphylococcus aureus and gram-positive bacteria. Lancet North American Edition. June 353(9170): 2129. {a} Department of Dermatology, University of Freiburg, Freiburg, D-79104, Germany

Schempp, C. M., H. B. Simon, et al. (1999). In vitro and in vivo activation of hypericin with the incoherent light source PDT 1200 SOA (520-750 nm) and with solar simulated radiation (290-2500 nm). Photodermatology Photoimmunology and Photomedicine 15(1): 13-17. {a} Dep. Dermatol., Hauptstr. 7, D-79104 Freiburg, Germany

Schempp, C. M., B. Winghofer, et al. (1999). Hypericin levels in human serum and interstitial skin blister fluid after oral single-dose and steady-state administration of Hypericum perforatum extract (St. John's wort). Skin Pharmacology and Applied Skin Physiology. Sept. Oct. 12(5): 299-304. {a} Department of Dermatology, University of Freiburg, Hauptstrasse 7, D-79104, Freiburg, Germany

Schempp, H., A. Denke, et al. (1999). Biochemical activities of extracts from Hypericum perforatum L.: 3rd communication: Modulation of peroxidase activity as a simple method for standardization. Arzneimittel Forschung. Feb. 49(2): 115-119. {a} Phytopathologie, Technische Universitaet Muenchen, D-85350, Freising-Weihenstephan, Germany

Shannon, M. (1999). Alternative medicines toxicology: A review of selected agents. Journal of Toxicology Clinical Toxicology. Oct. 37(6): 709-713. {a} Division of Emergency Medicine and Program in Clinical Pharmacology/Toxicology, Children's Hospital, 300 Longwood Avenue, Boston, MA, USA

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Singer, A., M. Wonnemann, et al. (1999). Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1. Journal of Pharmacology and Experimental Therapeutics. Sept. 290(3): 1363-1368. {a} Department of Pharmacology, Biocenter, University of Frankfurt, Marie-Curie-Str. 9, D-60439, Frankfurt Main, Germany

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Cott, J. Natural product formulations available in Europe for psychotropic indications. Psychopharmacology Bulletin 31(4): 745-751. NIMH, 5600 Fishers Lane, Room 18-105, Rockville, MD 20857, USA