Source: AGRICOLA database (1970-1996)

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Schmidt, P. and W. H. Boehncke (2000). Delayed-type hypersensitivity reaction to kava-kava extract. Contact Dermatitis. [print] June 42(6): 363-364. {a} Department of Dermatology, University of Frankfurt, Theodor-Stern-Kai 7, D-60590, Frankfurt, Germany

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Pittler, M. H. and E. Ernst (1999). Efficacy of kava extract for treating anxiety: Systematic review and meta-analysis. Journal of Clinical Psychopharmacology. Feb. 20(1): 84-89. {a} Department of Complementary Medicine, University of Exeter, 25 Victoria Park Road, Exeter, EX2 4NT, UK

Schirrmacher, K., D. Buesselberg, et al. (1999). Effects of (racemic)-kavain on voltage-activated inward currents of dorsal root ganglion cells from neonatal rats. European Neuropsychopharmacology 9(1-2): 171-176. {a} Inst. Physiol., Univ.-GH Essen, Hufelandstrasse 55, 45122 Essen, Germany

Boonen, G., B. Ferger, et al. (1998). In vivo effects of the kavapyrones (+)-dihydromethysticin and racemic-kavain on dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid levels in striatal and cortical brain regions. Planta Medica 64(6): 507-510. {a} Institut Pharmazeutische Biologie, Philipps-Universitaet, Deutschhausstr. 17A, D-35032 Marburg, Germany

Boonen, G. and H. Haeberlein (1998). Influence of genuine kavapyrone enantiomers on the GABAA binding site. Planta Medica 64(6): 504-506. Institut Pharmazeutische Biologie, Philipps-Universitaet, Deutschhausstr. 17 A, D-35032 Marburg, Germany

Friese, J. and J. Gleitz (1998). Kavain, dihydrokavain and dihydromethysticin non-competitively inhibit the specific binding of (3H)-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Planta Medica 64(5): 458-459. {a} Univ. Clinic Ulm, Inst. Naturheilkunde, Helmholtzstrasse 20, D-89081 Ulm, Germany

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Shao, Y., K. He, et al. (1998). Reversed-phase high-performance liquid chromatographic method for quantitative analysis of the six major kavalactones in Piper methysticum. Journal of Chromatography A 825(1): 1-8. {a} Dep. Res. and Dev., Madis Bot. Inc., 375 Huyler St., South Hackensack, NJ 07606, USA

Uebelhack, R., L. Franke, et al. (1998). Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava). Pharmacopsychiatry 31(5): 187-192. {a} Charite-Universitaetsklinikum, Medizinische Fak. Humboldt-Univ. Berlin, Klinik Psychiatrie, Schumannstr. 20-21, D-10117 Berlin, Germany

Wong, A. H. C., M. Smith, et al. (1998). Herbal remedies in psychiatric practice. Archives of General Psychiatry 55(11): 1033-1044. {a} Clarke Inst. Psychiatry, 250 College St., Toronto, ON M5T 1R8, Canada

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Gleitz, J., A. Beile, et al. (1997). Antithrombotic action of the kava pyrone (+)-kavain prepared from Piper methysticum on human platelets. Planta Medica 63(1): 27-30. {a} Universitaetsklin. Ulm, Inst. Naturheilkunde, Helmholtzstr. 20, D-89081 Ulm, Germany

Haeberlein, H., G. Boonen, et al. (1997). Piper methysticum: Enantiomeric separation of kavapyrones by high performance liquid chromatography. Planta Medica 63(1): 63-65. {a} Inst. Pharm. Biol. Philipps Univ., Deutschhausstr. 17A, D-35032 Marburg, Germany

He, X. G., L. Z. Lin, et al. (1997). Electrospray high performance liquid chromatography-mass spectrometry in phytochemical analysis of kava (Piper methysticum) extract. Planta Medica 63(1): 70-74. {a} Res. Lab. Nat. Products Chem., East Earth Herb Inc., 4091 W. 11th Ave., Eugene, OR 97402, USA

Lopez, A. V. and J. Benedicto (1997). Supercritical fluid extraction of kava lactones from Piper methysticum (kava) herb. HRC Journal of High Resolution Chromatography 20(10): 555-559. {a} Midwest Res. Inst., California Operations, Mountain View, CA 94043, USA

Seitz, U., A. Ameri, et al. (1997). Relaxation of evoked contractile activity of isolated guinea-pig ileum by (racemic)-kavain. Planta Medica 63(4): 303-306. {a} Dep. Pharm. Pharmacol. Nat. Compounds, Univ. Ulm, Helmholtzstr. 20, D-89081 Ulm, Germany

Walden, J., W. J. Von, et al. (1997). Actions of kavain and dihydromethysticin on ipsapirone-induced field potential changes in the hippocampus. Human Psychopharmacology 12(3): 265-270. {a} Dep. Psychiatry, Univ. Freiburg, Hauptstr. 5, 79104 Freiburg, Germany

Walden, J., W. J. Von, et al. (1997). Effects of Kawain and dihydromethysticin on field potential changes in the hippocampus. Progress in Neuro Psychopharmacology and Biological Psychiatry 21(4): 697-706. {a} Dep. Psychiatry, Univ. Freiburg, Hauptstr. 5, 79104 Freiburg, Germany

Davis, R. I. and J. F. Brown (1996). Epidemiology and management of kava dieback caused by cucumber mosaic cucumovirus. Plant Disease 80(8): 917-921. {a} Fac. Sci., Northern Territory Univ., Darwin, NT 0909, Australia

Davis, R. I., J. F. Brown, et al. (1996). Causal relationship between cucumber mosaic cucumovirus and kava dieback in the South Pacific. Plant Disease 80(2): 194-198. {a} Dep. Botany, Univ. New England, Armidale, NSW 2351, Australia

Gleitz, J., A. Beile, et al. (1996). (racemic)-Kavain inhibits the veratridine- and KCl-induced increase in intracellular Ca-2+ and glutamate-release of rat cerebrocortical synaptosomes. Neuropharmacology 35(2): 179-186. {a} Inst. Naturheilkunde, Univ. Clinics Ulm, Helmholtzstr. 20, 89070 Ulm, Germany

Gleitz, J., J. Friese, et al. (1996). Anticonvulsive action of (racemic)-kavain estimated from its properties on stimulated synaptosomes and Na+ channel receptor sites. European Journal of Pharmacology 315(1): 89-97. {a} Univ. Clinics Ulm, Inst. Naturheilkunde, Helmholtzstrasse 20, 89081 Ulm, Germany

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Lebot, V. and J. Levesque (1996). Evidence for conspecificity of Piper methysticum Forst. f. and Piper wichmannii C. DC. Biochemical Systematics and Ecology 24(7-8): 775-782. {a} CIRAD, B.P. 5035, 34032 Montpellier, France

Lebot, V. and J. Levesque (1996). Genetic control of kavalactone chemotypes in Piper methysticum cultivars. Phytochemistry Oxford 43(2): 397-403. CIRAD, PO Box 6, Pouembout, New Caledonia

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Suess, R. and P. Lehmann (1996). Hematogenous allergic contact dermatitis from kava, an herbal product. Hautarzt 47(6): 459-461. {a} Hautklin., Heinrich-Heine-Univ., Moorenstr. 5, D-40225 Duesseldorf, Germany

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Schelosky, L., C. Raffauf, et al. (1995). Kava and dopamine antagonism. Journal of Neurology Neurosurgery and Psychiatry 58(5): 639-640. Dep. Neurol., Univ. Rudolf Virchow, Augustenburgerplatz 1, 13 353 Berlin, Germany

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Marler, T. E., M. V. Mickelbart, et al. (1993). Papaya ringspot virus influences net gas exchange of papaya leaves. Hortscience 28(4): 322-324. Coll. Agric. Life Sci., Univ. Guam, Univ. Guam Station, Mangilao, Guam 96923

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Backhauss, C. and J. Krieglstein (1992). Extract of kava (Piper methysticum) and its methysticin constituents protect brain tissue against ischemic damage in rodents. European Journal Of Pharmacology 215(2-3): 265-269.

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